Reports suggest the Leicester City striker is prepared to move on without his wife, Jamila.
Musa is reported to be in love with another woman, who he is set to marry as a second wife. But the idea was rejected by Jamila.
Recently, Police in the United Kingdom stormed Musa's home and arrested the Super Eagles forward over disturbances, but released him hours later.
A top source told SCORE Nigeria: “Ahmed Musa has divorced his wife. He gave her Saki Uku (a final divorce notice).
“She is already back home in Kano trying to get her life together again.”
The marriage produced two children.
Musa has become less favoured at Leicester City in recent times, which has seen him miss several important fixtures.
The foxes will hope to continue their great form under new manager Craig Shakespeare.
They travel to Crystal Palace on Saturday with hope to get all three points. Leicester is currently placed 11 with 36 points from 31 matches.